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N-羥基丁二酰亞胺

更新時間:2019-04-24 點(diǎn)擊次數(shù):762次

N-羥基丁二酰亞胺

性質(zhì)

InChI Key  NQTADLQHYWFPDB-UHFFFAOYSA-N
assay  98%
mp  95-98 °C (lit.)

產(chǎn)品描述

包裝

1 kg in poly bottle

5 kg in poly drum

5, 25, 100, 250 g in poly bottle

Application

N-Hydroxysuccinimide can be used in the synthesis of N-hydroxysuccinimide ester via dehydration reaction in the presence of dicyclohexylcarbodiimide in carboxylic acid.

N-Hydroxysuccinimide has been used in the synthesis of intermediates such as:
• N

• -succinimidyl 3-(di-tert-butylfluorosilyl)benzoate
• 4-[2,2-bis[(p-tolylsulfonyl)-methyl] acetyl]benzoic acid-NHS ester
• N-succinimidyl 3-iodobenzoate

It has also been used in a protocol for the surface modification of microchannels of a microfluidic-integrated surface plasmon resonance (SPR) platform for the detection and quantification of bacterial pathogens.

Additive used in the carbodiimide method for improved amidations and peptide couplings.

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